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Never directly onto the lyophilised puck, which causes protein shearing and irreversible aggregation

Cytostatic agents, particularly platinum-based drugs such as topotecan and cisplatin, have been linked to the induction of eryptosis, thereby worsening anemia [392, 393]

The main advantage of IVs is that they are absorbed at 100% efficiency as it bypasses the digestive system and goes right into the veins

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Nevertheless, due to the requirement of prolonged parenteral administration, patients' compliance with DFO is limited (121)